Background: Anxiety and stress are important risk factors for psycho-somatic DISORDERS like GASTROINTESTINAL DISORDERS. The main purpose of this study is to investigate the relationship between anxiety and stress with FUNCTIONAL GASTROINTESTINAL DISORDERS (FGID). Materials and Methods: This study was a descriptive-analytical one with a correlation method. In this study, 82 patients with FGID who were referred to Noor Hospital of Isfahan in 2019 were selected and evaluated with anxiety and stress scale (HASS) and severity of GASTROINTESTINAL symptoms scale. Data were analyzed with descriptive statistics, Pearson correlation, and multivariate regression. Results: The results showed that there was a significant positive relationship between anxiety and stress with the severity of GASTROINTESTINAL symptoms in these patients, and anxiety could predict changes in the severity of GASTROINTESTINAL symptoms very well. Conclusion: According to the findings of the study on the correlation between anxiety and stress with the severity of GASTROINTESTINAL symptoms in patients with FUNCTIONAL DISORDERS, in the treatment of these patients should pay attention to the areas of anxiety and stress and minimize these aggravating factors with psychological measures. es.

Introduction: FUNCTIONAL GASTROINTESTINAL DISORDERS (FGIDs) represent the most prevalent condition in patients who come to medical clinics with abdominal symptoms. Several studies have shown that psychiatric comorbidity, including mood and anxiety DISORDERS, is highly prevalent in patients with FGIDs. Personality traits can cause FUNCTIONAL symptoms in a variety of diseases. However, limited studies have assessed personality characteristics in FGIDs patients. Therefore, the purpose of the present research was to compare personality traits between patients with FGIDs and healthy people based on the five-factor personality model. Materials and Methods: In this case-control study, 40 patients referred to the psychosomatic clinic of Booali Sina Hospital, Qazvin, Iran, from September 2019 to March 2020 and diagnosed as FGIDs and 40 healthy individuals were participated. After a clinical interview with a psychiatrist, all participants completed the NEO-Five Factor Inventory (NEO-FFI). The data was analyzed using Chi-square test, independent t-test, and the Pearson correlation test. Results: The results showed that the mean neuroticism score in patients with FGIDs was significantly higher than that of healthy individuals (P= 0. 000). Also, FGID cases had significantly lower extraversion (P= 0. 000), conscientiousness (P= 0. 005), openness to experiences (P= 0. 023), and agreeableness (P= 0. 000) scores compared to healthy subjects. Conclusion: The results of this research indicated personality differences between patients with FUNCTIONAL GASTROINTESTINAL DISORDERS and healthy individuals. If further studies confirm this finding, new psychological interventions focused on personality characteristics may be introduced to treat FUNCTIONAL GASTROINTESTINAL DISORDERS.